Genotoxicity Evaluation of Ten Nitrosamine Drug Substance-Related Impurities Using 2D and 3D HepaRG Cell Models

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Author/s:Seo, Ji-Eun; Xu, Hannah; Li, Xilin; Atrakchi, Aisar H; McGovern, Timothy; Davis Bruno, Karen L; Keire, David A; Mei, Nan; Heflich, Robert H; Guo, Xiaoqing

Date:11/01/2025

Journal:Regulatory Toxicology and Pharmacology: RTP

DOI:10.1016/j.yrtph.2025.105906