Bumetanide as a Model NDSRI Substrate: N-nitrosobumetanide Impurity Formation and its Inhibition in Bumetanide Tablets

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Author/s:Shakleya, Diaa; Asmelash, Bethel; Alayoubi, Alaadin; Abrigo, Nicholas; Mohammad, Adil; Wang, Jiang; Zhang, Jinhui; Yang, Jingyue; Marzan, Tim; Li, David; Shaklah, Maha; Alsharif, Fahd M; Desai, Saaniya; Faustino, Patrick J; Muhammad, Ashraf; O’connor, Thomas; Vera, Matthew; Raw, Andre; Sayeed, Vilayat; Keire, David

Date:

Journal:Journal of Pharmaceutical Sciences

DOI:https://doi.org/10.1016/j.xphs.2023.06.013